Best Bets for NCAA Basketball Picks Against the Spread for Friday, February 21

Published 11:22 pm Thursday, February 20, 2025

The Kent State Golden Flashes versus the Miami (OH) RedHawks is one of many compelling options on Friday in college basketball action — suggested picks against the spread for 10 games are available below.

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Today’s NCAA Men’s Basketball Picks ATS

ATS Pick: Kent State +1.5 vs. Miami (OH)

  • Matchup: Kent State Golden Flashes at Miami (OH) RedHawks
  • Time: 8 p.m. ET
  • Date: February 21
  • Computer Projection: Kent State by 2.6 points (Bet now on BetMGM)
  • Spread: Miami (OH) (-1.5)
  • TV Channel: CBS Sports Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Purdue Fort Wayne -3.5 vs. Oakland

  • Matchup: Oakland Golden Grizzlies at Purdue Fort Wayne Mastodons
  • Time: 7 p.m. ET
  • Date: February 21
  • Computer Projection: Purdue Fort Wayne by 6.9 points (Bet now on BetMGM)
  • Spread: Purdue Fort Wayne (-3.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Yale -9.5 vs. Cornell

  • Matchup: Cornell Big Red at Yale Bulldogs
  • Time: 7 p.m. ET
  • Date: February 21
  • Computer Projection: Yale by 12.2 points (Bet now on BetMGM)
  • Spread: Yale (-9.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Manhattan +2.5 vs. Iona

  • Matchup: Manhattan Jaspers at Iona Gaels
  • Time: 7 p.m. ET
  • Date: February 21
  • Computer Projection: Iona by 0.4 points (Bet now on BetMGM)
  • Spread: Iona (-2.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Wright State -3.5 vs. Northern Kentucky

  • Matchup: Northern Kentucky Norse at Wright State Raiders
  • Time: 7 p.m. ET
  • Date: February 21
  • Computer Projection: Wright State by 5.6 points (Bet now on BetMGM)
  • Spread: Wright State (-3.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

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ATS Pick: Merrimack -6.5 vs. Sacred Heart

  • Matchup: Sacred Heart Pioneers at Merrimack Warriors
  • Time: 7 p.m. ET
  • Date: February 21
  • Computer Projection: Merrimack by 8.5 points (Bet now on BetMGM)
  • Spread: Merrimack (-6.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Marquette -1.5 vs. Villanova

  • Matchup: Marquette Golden Eagles at Villanova Wildcats
  • Time: 7 p.m. ET
  • Date: February 21
  • Computer Projection: Marquette by 3.5 points (Bet now on BetMGM)
  • Spread: Marquette (-1.5)
  • TV Channel: Fox Sports 1
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Dartmouth -1.5 vs. Pennsylvania

  • Matchup: Dartmouth Big Green at Pennsylvania Quakers
  • Time: 7 p.m. ET
  • Date: February 21
  • Computer Projection: Dartmouth by 3.3 points (Bet now on BetMGM)
  • Spread: Dartmouth (-1.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Niagara +6.5 vs. Siena

  • Matchup: Niagara Purple Eagles at Siena Saints
  • Time: 7 p.m. ET
  • Date: February 21
  • Computer Projection: Siena by 4.7 points (Bet now on BetMGM)
  • Spread: Siena (-6.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

ATS Pick: Detroit Mercy +8.5 vs. Cleveland State

  • Matchup: Cleveland State Vikings at Detroit Mercy Titans
  • Time: 7 p.m. ET
  • Date: February 21
  • Computer Projection: Cleveland State by 6.9 points (Bet now on BetMGM)
  • Spread: Cleveland State (-8.5)
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

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